Parag Singhal , Andrea Caumo , Peter E . Carey , Claudio Cobelli and Roy Taylor mixed meal in type 2 diabetes Regulation of endogenous glucose production after a
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[PDF] [Full Text] [Abstract] , November 1, 2008; 295 (5): E1132-E1141. Am J Physiol Endocrinol Metab Bouwman, Matthew J. Watt, Joseph Proietto, Jenny M. Favaloro and Sofianos Andrikopoulos Sherley Visinoni, Barbara C. Fam, Amy Blair, Christian Rantzau, Benjamin J. Lamont, Russell the liver Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in [PDF] [Full Text] [Abstract] 2008; 31 (11): 2183-2187. Dia Care and David B. Dunger Mary E. Pennant, Leslie J.C. Bluck, M. Loredana Marcovecchio, Burak Salgin, Roman Hovorka Insulin Administration and Rate of Glucose Appearance in People With Type 1 Diabetes [PDF] [Full Text] [Abstract] , April , 2009; 329 (1): 102-111. J Pharmacol Exp Ther Véniant Y. Lau, Jin Wang, Yue-Sheng Li, Tom Boone, Richard A. Lindberg, Sylvia Hu and Murielle M. Renée Komorowski, Cheng Zhang, Jennifer J. Patel, Dorothy Caughey, Gary S. Elliott, Yvonne Hai Yan, Wei Gu, Jie Yang, Vivian Bi, Yuqing Shen, Eunkyung Lee, Katherine A. Winters, Glucose Homeostasis in Mice and Monkeys Fully Human Monoclonal Antibodies Antagonizing the Glucagon Receptor Improve [PDF] [Full Text] [Abstract] , May , 2009; 32 (5): 866-872. Dia Care Rizza Ananda Basu, Chiara Dalla Man, Rita Basu, Gianna Toffolo, Claudio Cobelli and Robert A. Postprandial Glucose Metabolism Effects of Type 2 Diabetes on Insulin Secretion, Insulin Action, Glucose Effectiveness, and [PDF] [Full Text] [Abstract] , December , 2009; 331 (3): 871-881. J Pharmacol Exp Ther Richard A. Lindberg and Murielle M. Véniant Atangan, Glenn Sivits, David Hill, Jie Yang, Vivian Bi, Yuqing Shen, Sylvia Hu, Tom Boone, Wei Gu, Hai Yan, Katherine A. Winters, Renée Komorowski, Steven Vonderfecht, Larissa and Hyperglucagonemia -Cell Hyperplasia α Causes Sustained Improvement in Glycemic Control, with Reversible Long-Term Inhibition of the Glucagon Receptor with a Monoclonal Antibody in Mice
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Regulation of endogenous glucose production after a mixed meal in type 2 diabetes.
The extent and time course of suppression of endogenous glucose production (EGP) in type 2 diabetes after a mixed meal have been determined using a new tracer methodology. Groups of age-, sex-, and weight-matched normal controls (n = 8) and diet-controlled type 2 diabetic subjects (n = 8) were studied after ingesting a standard mixed meal (550 kcal; 67% carbohydrate, 19% fat, 14% protein). Ther...
متن کاملAcute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production.
To test the hypothesis that intrahepatic availability of fatty acid could modify the rate of suppression of endogenous glucose production (EGP), acipimox or placebo was administered before and during a test meal. We used a modified isotopic methodology to measure EGP in 11 healthy subjects, and (1)H magnetic resonance spectroscopic measurement of hepatic triglyceride stores was also undertaken....
متن کاملAssessment of -cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests
Claudio Cobelli, Gianna Maria Toffolo, Chiara Dalla Man, Marco Campioni, Paolo Denti, Andrea Caumo, Peter Butler, and Robert Rizza Department of Information Engineering, University of Padua, Padua, Italy; San Raffaele Scientific Institute, Milan, Italy; Larry Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, California; and Division of Endoc...
متن کاملE-00421-2006.r1 Assessment of Beta Cell Function in Humans, Simultaneously with Insulin Sensitivity and Hepatic Extraction, from Intravenous and Oral Glucose Test
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Effects of Type 2 Diabetes on Insulin Secretion, Insulin Action, Glucose Effectiveness, and Postprandial Glucose Metabolism
OBJECTIVE In this study, we sought to determine whether postprandial insulin secretion, insulin action, glucose effectiveness, and glucose turnover were abnormal in type 2 diabetes. RESEARCH DESIGN AND METHODS Fourteen subjects with type 2 diabetes and 11 nondiabetic subjects matched for age, weight, and BMI underwent a mixed-meal test using the triple-tracer technique. Indexes of insulin sec...
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